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Fundamentinių mokslų fakultetas / Faculty of Fundamental Sciences >
Moksliniai straipsniai / Research articles >
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http://dspace.vgtu.lt/handle/1/211
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| Title: | Modelling a peroxidase-based optical biosensor |
| Authors: | Baronas, Romas
Gaidamauskaitė, Evelina
Kulys, Juozas |
| Keywords: | Optical biosensor
Peroxidase
Modelling
Simulation |
| Issue Date: | 2007 |
| Publisher: | Basel : MDPI. |
| Citation: | Baronas, R.; Gaidamauskaitė, E.; Kulys, J. 2007. Modelling a peroxidase-based optical biosensor, Sensors 7: 2723-2740. |
| Abstract: | The response of a peroxidase-based optical biosensor was modelled digitally. A mathematical model of the optical biosensor is based on a system of non-linear reactiondiffusion equations. The modelling biosensor comprises two compartments, an enzyme layer and an outer diffusion layer. The digital simulation was carried out using finite difference technique. The influence of the substrate concentration as well as of the thickness of both the enzyme and diffusion layers on the biosensor response was investigated. Calculations showed complex kinetics of the biosensor response, especially at low concentrations of the peroxidase and of the hydrogen peroxide. |
| URI: | http://dspace1.vgtu.lt/handle/1/211 |
| ISSN: | 1424-8220 |
| Appears in Collections: | Moksliniai straipsniai / Research articles
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