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Title: Design and optimization of pulsed magnetic field generator for cell magneto- permeabilization
Authors: Novickij, Vitalij
Grainys, Audrius
Staigvila, Gediminas
Tolvaišienė, Sonata
Ustinavičius, Tomas
Novickij, Jurij
Keywords: Pulsed power
transient process
Issue Date: 2017
Publisher: Elektronika ir elektrotechnika
Citation: Novickij, V.; Grainys, A.; Staigvila, G.; Tolvaisiene, S.; Ustinavicius,T.; Novickij, J. 2017. Design and optimization of pulsed magnetic field generator for cell magneto- permeabilization. Elektronika ir elektrotechnika, 23(2),21-25.
Series/Report no.: 23;2
Abstract: Biological cell magneto-permeabilization is the phenomenon when the membrane of the cell increases permeability to molecules to which it was initially impermeable due to the exposure to high pulsed magnetic fields. Flexible high power electronics systems are required for triggering this effect. In this work, we have designed a high power (938 A, 2 kV) pulsed magnetic field generator (up to 5.5 T), which generates 10 μs–100 μs pulses with predefined repetition frequency of 1 Hz–100 Hz. We have applied SPICE and COMSOL Multiphysics modelling for design and development of the system, which showed a good agreement with the experimental results. The snubber and crowbar circuitry has been implemented for compensation and dampening of the transient processes on the switches, which allowed limiting the overvoltage to 0.25 kV. The multilayer inductor structure and design considerations are also presented in the study.
ISSN: 1392-1215
Appears in Collections:Moksliniai straipsniai / Research articles

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